Autophagy, an efficient and effective approach to clear rapidly damaged organelles, macromolecules, and other harmful cellular components, enables the recycling of nutrient materials and supply of nutrients to maintain cellular homeostasis.Ubiquitination plays an important regulatory role in autophagy.This paper summarizes the most recent progress

Fluorescence-guided resections have become standard of care for malignant gliomas.Strong fluorescence has been shown to correlate with solid enhancing tumor.However, with experience it has also been shown that visualized fluorescence may not identify the entire extent of the tumor.Knowing that malignant gliomas extend beyond the contrast-enhancing

Animal models should display important characteristics of the human disease.Sheep have been considered particularly useful to study allergic airway responses to common natural antigens causing human asthma.A rationale of this study was to establish a model of ovine precision-cut lung slices (PCLS) for the in vitro measurement of airway responses in